PROGRAMME

SATURDAY October 4 th.

2:00-5:00pm

Registration – Villa Lanna

5:00-6:00pm

Dinner lecture

PI 3-kinase, oncoprotein and cancer target

Peter Vogt

6:30-8:00pm

Welcome dinner

SUNDAY October 5 th

9:30–12:30

Assembly and structure - 20min. talks + 10min. discussion

Chair: Raymond F. Schinazi, Rebecca Craven

TWO MOLECULAR SWITCHES REQUIRED FOR IMMATURE ASSEMBLY IN ROUS SARCOMA VIRUS.

Volker M. Vogt 12

COMPARISON OF MLV GAG TO HIV-1 GAG

Alan Rein 13

ELECTRON CRYOTOMOGRAPHY OF HIV-1

Elizabeth R. Wright 14

A revised model for HIV-1 morphogenesis

Hans-Georg Kräusslich 15

Short talks – 10min. talks + 5min. discussion

A novel model for assembly of retroviral cores

Ila Singh 48

Structure and arrangement of Gag in immature retroviruses

John Briggs 41

IN VITRO STUDIES OF RETROVIRAL CAPSID NUCLEATION

Rebecca Craven 42

GENERAL DISCUSSION

12:30-2:00pm

Lunch

SUNDAY October 5 th cont.

2:00-5:30pm

Targeting - 20min. talks + 10min. discussion

Chair: Axel Rethwilm, Volker Vogt

THE INTERPLAY BETWEEN ENDOGENOUS AND EXOGENOUS RETROVIRUSES IN THE DOMESTIC SHEEP.

Massimo Palmarini 17

CELLULAR MACHINERY IN HIV-1 GAG TRAFFICKING AND VIRUS ASSEMBLY

Eric O. Freed 18

HIV GAG PROTEIN TRAFFICKING IN LIVING CELLS

Paul Spearman 19

interactions of Mason-Pfizer monkey virus matrix protein that control polyprotein targeting and particle budding

Tomas Ruml 20

CONSTRUCTION OF A MASON-PFIZER MONKEY VIRUS GAG-GFP FUSION: VISUALIZATION OF VIRAL CAPSID ASSEMBLY AND TRANSPORT IN LIVE CELLS

Eric Hunter 21

Short talk – 10min. talk + 5min. discussion

THE HIV ASSEMBLY COMPARTMENT IN HUMAN MACROPHAGES

Annegret Pelchen-Matthews 57

GENERAL DISCUSSION

6:30-7:30pm

Dinner

8:00pm

Concert

MONDAY October 6 th.

9:30–12:30

Packaging - 20min. talks + 10min. discussion

Chair: Hans-Georg Kräusslich, Iva Pichová

FOAMY VIRUS ASSEMBLY AND POL PACKAGING

Maxine Linial 23

Packaging the RNA Genome of Influenza A Virus

Tristram G. Parslow 24

RNA PACKAGING IN LENTIVIRUSES

Andrew Lever 25

Short talks – 10min. talks + 5min. discussion

HIV-2 GENOME DIMERISATION AND VIRAL INFECTIVITY: A CRITICAL ROLE FOR THE PACKAGING SIGNAL AND STEM-LOOP 1

Anne L'Hernault 61

STRUCTURAL AND FUNCTIONAL STUDIES OF THE MOLONEY MURINE LEUKEMIA VIRUS READTHROUGH SIGNAL

Victoria D'Souza 60

GENERAL DISCUSSION

12:30-2:00pm

Lunch

2:00pm-6:00pm

Excursion - Prague

6:30–8:00pm

Dinner

TUESDAY October 7 th.

9:30–12:30

Env interactions and budding

- 20min. talks + 10min. discussion

Chair: Eric Hunter, Maxine Linial

Diverse mechanisms for recruiting Env to viral assembly sites.

Marc C Johnson 27

CRYOELECTRON TOMOGRAPHY OF HIV AND SIV ENVELOPE SPIKES AND ASSOCIATED LIGANDS

Kenneth H. Roux 28

RESCUE OF HIV BUDDING BY ALIX AND NEDD4-2S

Heinrich Göttlinger 29

Short talks – 10min. talks + 5min. discussion

DETERMINANTS FOR LOCALIZATION OF HIV-1 GAG AT THE PLASMA MEMBRANE

Akira Ono 55

THE N-TERMINAL COILED-COIL DOMAIN OF PROTOTYPE FOAMY VIRUS GAG IS ESSENTIAL FOR VIRAL PARTICLE EGRESS AND GLYCOPROTEIN INTERACTION

Dirk Lindemann 65

GENERAL DISCUSSION

12:30-2:00pm

Lunch

4:00-6:30pm

Poster session

7:00-9:00pm

Farewell dinner

WEDNESDAY October 8 th.

9:00-12:00

Virus interactions with host defense mechanisms

- 20min. talks + 10min. discussion

Chair: Heinrich Gottlinger, Massimo Palmarini

Cell-to-cell transmission of HIV-1: the role(s) of tetraspanins

Markus Thali 31

HIV-1 Vif and Vpu target intrinsic and innate antiretroviral host defense mechanisms

Klaus Strebel 32

VIRION-ASSOCIATED SIVMAC VPX PROTECTS HIV-1 FROM THE TYPE I INTERFERON RESPONSE

Jeremy Luban 33

Short talks – 10min. talks + 5min. discussion

APOBEC3G Virion Incorporation: Intracellular Interactions Between APOBEC3G, RNA, and HIV-1 Gag

Vinay Pathak 69

ROLE OF VPU IN HIV-1 PARTICLE RELEASE

Alexei Karetnikov 68

Identification of Post-entry Restrictions to Mason-Pfizer Monkey Virus Infection in New World Monkey Cells

Eric Hunter 71

GENERAL DISCUSSION

2:00pm

Departure to satellite meeting – Mělník/Liblice

7:00pm?

Dinner – Chateau Liblice

THURSDAY October 9 th.

Satellite meeting

9:00-12:00

Assembly as a Therapeutic Target

- 20min. talks + 10min. discussion

Chair: Elizabeth Wright, Tomas Ruml

STRUCTURAL BASIS FOR MEMBRANE TARGETING BY HIV-1 GAG

Michael F. Summers 35

BIOPHYSICAL STUDIES OF HIV ASSEMBLY AND MATURATION

Peter Prevelige 36

MAPPING OF THE BINDING SITE FOR THE MATURATION INHIBITOR BEVIRIMAT WITHIN HIV-1 GAG PARTICLES

Michael Sakalian 37

GENERAL DISCUSSION

12:30-2:00pm

Lunch

3:00 pm

Departure to Prague – expected arrival to Prague ~ 5:00 pm